Table S1. Distant metastases according to depth of tumor invasion.
| Distant metastatic sites | Total patients (No.) | sm1* (5 patients) | sm2* (5 patients) | sm3* (12 patients) |
|---|---|---|---|---|
| Brain | 1 | 0 | 0 | 1 |
| Cervical lymph nodes | 6 | 2 | 0 | 4 |
| Larynx | 1 | 1 | 0 | 0 |
| Lung | 5 | 1 | 3 | 1 |
| Abdomen | 1 | 0 | 0 | 1 |
| Liver | 2 | 0 | 1 | 1 |
| Adrenal gland | 1 | 0 | 0 | 1 |
| Multiple metastases** | 2 | 0 | 0 | 2 |
| Unclear | 3 | 1 | 1 | 1 |
sm1, inner third submucosa; sm2, middle third submucosa; sm3, deep third submucosa. *, no significant differences were detected (sm3 vs. sm2, P=0.353; sm3 vs. sm1, P=0.338). **, indicates metastases at more than two sites.