Table S2. Risks of lymph node metastasis, recurrence, and death according to depth of tumor, presence of lymphovascular invasion and pathology grade.
| Depth | LVI | Total cases | Pathology grade (W/M/P) | LN positive (%) | Recurrence (%)* | Death (%)* | Recurrence or death (%)** | Odds ratio | 95% confidence interval | P value† |
|---|---|---|---|---|---|---|---|---|---|---|
| sm1 | − | 69 | 1 | 0/1 (0) | 0/1 (0) | 0/1 (0) | 0/1 (0) | 30.000 | 3.130–287.500 | 0.003 |
| 45 | 1/45 (2.2) | 1/40 (2.5) | 4/40 (10) | 5/40 (12.5) | ||||||
| 23 | 4/23 (17.4) | 3/22 (13.6) | 3/22 (13.6) | 4/22 (18.2) | ||||||
| + | 6 | 1 | 1/1 (100.0) | 0/1 (0) | 0/1 (0) | 0/1 (0) | ||||
| 3 | 2/3 (66.7) | 2/3 (66.7) | 1/3 (33.3) | 3/3 (100.0) | ||||||
| 2 | 1/2 (50.0) | 1/2 (50.0) | 1/2 (50.0) | 2/2 (100.0) | ||||||
| sm2 | − | 70 | 1 | 0/1 (0) | 0/1 (0) | 0/1 (0) | 0/1 (0) | NA | NA | NA |
| 50 | 7/50 (14.0) | 9/46 (19.6) | 7/46 (15.2) | 13/46 (28.3) | ||||||
| 19 | 0/19 (0) | 2/18 (11.1) | 1/18 (5.6) | 3/18 (16.7) | ||||||
| + | 3 | 0 | 0/0 (NA) | 0/0 (NA) | 0/0 (NA) | 0/0 (NA) | ||||
| 2 | 1/2 (50.0) | 0/1 (0) | 0/1 (0) | 0/1 (0) | ||||||
| 1 | 0/1 (0) | 0/1 (0) | 0/1 (0) | 0/1 (0) | ||||||
| sm3 | − | 101 | 2 | 0/2 (0) | 0/2 (0) | 0/2 (0) | 0/2 (0) | 0.689 | 0.131–3.618 | 0.498 |
| 54 | 7/54 (13.0) | 11/51 (21.6) | 7/51 (13.7) | 14/51 (27.5) | ||||||
| 45 | 12/45 (26.7) | 11/39 (28.2) | 8/39 (20.5) | 16/39 (41.0) | ||||||
| + | 9 | 0 | 0/0 (NA) | 0/0 (NA) | 0/0 (NA) | 0/0 (NA) | ||||
| 2 | 1/2 (50.0) | 0/2 (0) | 0/2 (0) | 0/2 (0) | ||||||
| 7 | 3/7 (42.9) | 2/6 (33.3) | 0/6 (0) | 2/6 (33.3) |
NA, not applicable; *, deducts lost patients; **, includes overlaps; †, Fisher’s exact test. P value indicates the impact of presence of lymphovascular invasion on recurrence or death according to each depth.