Table 1. Patient Characteristics.
| Characteristics | F0 (n = 30) | F1 (n = 45) | F2 (n = 58) | F3 (n = 33) | F4 (n = 21) |
|---|---|---|---|---|---|
| Sex (male/female) | 18/12 | 25/20 | 35/23 | 23/10 | 13/8 |
| Age (year) | 33.4 ± 5.8 | 29.6 ± 12.0 | 30.2 ± 12.4 | 35.36 ± 11.70 | 40.4 ± 11.3 |
| BMI (kg/m2) | 22.5 ± 1.2 | 26.3 ± 1.4 | 23.5 ± 0.85 | 21.2 ± 1.7 | 18.6 ± 1.3 |
| HBV-DNA (IU/mL) | < 103 | 9.6 × 106 | 3.3 × 106 | 1.7 × 106 | 2.0 × 106 |
| HBeAg (+/-) | 0/30 | 34/11 | 38/20 | 26/7 | 13/8 |
| SWV (m/s) | 1.11 ± 0.15 | 1.33 ± 0.19 | 1.49 ± 0.33 | 1.59 ± 0.27 | 2.32 ± 0.58 |
| ALT (IU/L) | 22.3 ± 5.1 | 49.1 ± 51.9 | 43.7 ± 46.4 | 74.8 ± 74.3 | 83.1 ± 91.9 |
| AST (IU/L) | 19.1 ± 3.4 | 45.7 ± 64.3 | 54.1 ± 108.7 | 71.1 ± 113.8 | 82.9 ± 109.4 |
| GGT (IU/L) | 18.5 ± 2.0 | 31.2 ± 25.4 | 37.7 ± 54.5 | 63.8 ± 71.8 | 116.7 ± 120.7 |
| PLT (109/L) | 202.2 ± 22.6 | 152.4 ± 48.4 | 147.0 ± 55.2 | 151.3 ± 49.8 | 97.4 ± 50.7 |
| HA (ng/mL) | 35.4 (32.2) | 47.1 (55.1) | 64.8 (74.2) | 64.5 (58.1) | 164.0 (350.7) |
| PCIII (ng/mL) | 4.2 (2.7) | 4.2 (2.2) | 4.3 (2.5) | 4.0 (2.9) | 6.4 (8.7) |
| CIV (ng/mL) | 38.1 (26.6) | 46.8 (34.6) | 60.6 (41.8) | 56.6 (50.0) | 129.3 (189.8) |
| LN (ng/mL) | 55.9 (38.8) | 89.6 (43.2) | 85.9 (29.0) | 78.6 (35.9) | 95.8 (50.5) |
ALT, AST, GGT, PLT, SWV: (mean ± standard deviation); CIV, HA, LN, PCIII: median (interquartile range); F0: control group. ALT = alanine aminotransferase, AST = aspartate amino-transferase, BMI = body mass index, CIV = collagen type IV, GGT = gamma-glutamyltransferase, HA = hyaluronic acid, HBV-DNA = hepatitis B virus-deoxyribonucleic acid, LN = laminin, PCIII = procollagen type III, PLT = platelet, SWV = shear-wave velocity