Table 3. Comparison of Non-Invasive Tests in Diagnosis of Liver Fibrosis Stage.
| F ≥ 1 | F ≥ 2 | F ≥ 3 | F = 4 | |
|---|---|---|---|---|
| AUC | ||||
| SWV | 0.913 | 0.851 | 0.854 | 0.965 |
| HA | 0.701 | 0.668 | 0.675 | 0.741 |
| PCIII | 0.524 | 0.550 | 0.591 | 0.752 |
| CIV | 0.690 | 0.671 | 0.693 | 0.804 |
| LN | 0.744 | 0.562 | 0.548 | 0.662 |
| Statistical comparison between AUC values* | ||||
| SWV vs. HA | 0.001* | 0.001* | 0.001* | 0.001* |
| SWV vs. PCIII | < 0.001* | < 0.001* | < 0.001* | < 0.001* |
| SWV vs. CIV | < 0.001* | < 0.001* | 0.001* | 0.005 |
| SWV vs. LN | 0.002* | < 0.001* | < 0.001* | < 0.001* |
| HA vs. PCIII | 0.014 | 0.038 | 0.040 | 0.845 |
| HA vs. CIV | 0.669 | 0.957 | 0.493 | 0.241 |
| HA vs. LN | 0.596 | 0.044 | 0.021 | 0.302 |
| PCIII vs. CIV | 0.044 | 0.027 | 0.042 | 0.210 |
| PCIII vs. LN | 0.005 | 0.551 | 0.478 | 0.242 |
| CIV vs. LN | 0.335 | 0.036 | 0.011 | 0.085 |
*Data are p values, which are significant when < 0.005, i.e., Bonferroni correction for multiple comparisons. AUC = area under receiver-operating characteristic curve, CIV = collagen type IV, HA = hyaluronic acid, LN = laminin, PCIII = procollagen type III, SWV = shear-wave velocity, vs. = versus