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. 2016 Apr 8;173(10):1678–1692. doi: 10.1111/bph.13469

Figure 4.

Figure 4

Locally administered KT109 reverses LPS‐induced allodynia. (A) Intraplantar KT109 reverses LPS‐induced allodynia in a dose‐related manner that persists up to 24 h (P < 0.001). A contralateral injection of 12 μg KT109 does not reverse LPS‐induced allodynia at any time point. (B) KT109 (12 μg) administered i.t. does not reverse LPS‐induced allodynia. (C) KT109 (12 μg) administered i.c.v. does not reverse LPS‐induced allodynia. *P < 0.05 versus LPS + vehicle. Data represent mean ± SEM, n = 6 mice per group.