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. 2016 Mar 23;173(10):1589–1601. doi: 10.1111/bph.13460

Figure 4.

Figure 4

The overexpression of SIRT1 inhibited the expression the Col1, Col3 and α‐SMA. After the infection of SIRT1 shRNA, resveratrol did not change the expression of the three molecules. (A) The effects of Lv‐SIRT1 infection on the expression of Col1, Col3 and α‐SMA in hypertrophic scar‐derived fibroblasts were detected by western blot (n = 6). (B) Representative western blot analysis for Col1, Col3 and α‐SMA protein levels after treatment with SIRT1 shRNA and resveratrol (n = 6). Resv, resveratrol. The results represent the mean ± SEM of six independent experiments. *P < 0.05.