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. 2016 Apr 5;173(10):1639–1652. doi: 10.1111/bph.13465

Figure 6.

Figure 6

Characteristics of currents through WT TASK‐2, TASK‐2_T108C and TASK‐2_T108P channels in varying concentrations of extracellular potassium (K+). (A) Currents recorded through wild‐type TASK‐2 channels in 2.5 mM K+, 25 mM K+ and 147.5 mM K+. Currents evoked by ramp changes in voltage from −120 to +20 mV, as detailed in Methods. (B) Currents recorded through TASK‐2_T108C channels in 2.5 mM K+, 25 mM K+ and 147.5 mM K+. (C) Currents recorded through TASK‐2_T108P channels in 2.5 mM K+, 25 mM K+ and 147.5 mM K+. (D) Plot of reversal potential versus external K+ concentration for WT TASK‐2, TASK‐2_T108C and TASK‐2_T108P.