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. 2016 Apr 5;173(10):1639–1652. doi: 10.1111/bph.13465

Figure 7.

Figure 7

Effect of changes in extracellular pH on mutant TASK‐2 channels. (A) Representative time course for enhancement and inhibition of outward current by extracellular alkalization and acidification, respectively, through TASK‐2_T108C channels. (B) TASK‐2_T108C currents evoked by ramp changes in voltage in control solution (pH 7.4), pH 8.4 and pH 6.4. (C) Representative time course for changes of outward current by extracellular alkalization through TASK‐2_T108P channels. (D) TASK‐2_T108P currents evoked by ramp changes in voltage in control solution (pH 7.4) and in alkaline solution (pH 8.4).