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. 2016 Apr 25;6:24974. doi: 10.1038/srep24974

Table 2. Association of two SNPs with Behçet’s Disease.

Gene SNP Stage Genotype/Allele BD
Controls
P Value Pc Value OR (95% CI)
N % N %
ITGAX (CD11c) rs2929 First AA 15 3.8 23 3.8 0.986 NS 1.01 (0.52–1.95)
AG 82 21.0 193 32.0 1.453 × 10−4 0.019 0.56 (0.42–0.76)
GG 294 75.2 387 64.2 2.606 × 10−4 0.034 1.69 (1.27–2.25)
G 670 85.7 967 80.2 0.002 NS 1.48 (1.16–1.89)
Second AA 12 1.6 40 2.7 0.107 NS 0.59 (0.31–1.13)
AG 180 23.7 470 31.3 1.974 × 10−4 1.184 × 10−3 0.69 (0.56–0.84)
GG 566 74.7 994 66.1 3.135 × 10−5 1.881 × 10−4 1.51 (1.24–1.84)
G 1312 86.5 2458 81.7 3.904 × 10−5 7.808 × 10−5 1.44 (1.21–1.71)
Combined AA 27 2.3 63 3.0 0.287 NS 0.78 (0.50–1.23)
AG 262 22.8 663 31.5 1.618 × 10−7 2.087 × 10−5 0.64 (0.55–0.76)
GG 860 74.8 1381 65.5 4.320 × 10−8 5.573 × 10−6 1.56 (1.33–1.84)
G 1982 86.2 3425 81.3 3.252 × 10−7 1.398 × 10−5 1.45 (1.25–1.67)
CD6 rs11230563 First CC 252 64.5 468 77.6 5.721 × 10−6 7.380 × 10−4 0.52 (0.39–0.69)
CT 128 32.7 121 20.1 6.685 × 10−6 8.624 × 10−4 1.94 (1.45–2.59)
TT 11 2.8 14 2.3 0.629 NS 1.22 (0.55–2.71)
C 632 80.8 1057 87.6 3.189 × 10−5 1.371 × 10−3 0.59 (0.46–0.76)
Second CC 501 66.1 1137 75.6 1.811 × 10−6 1.087 × 10−5 0.63 (0.52–0.76)
CT 238 31.4 349 23.2 2.714 × 10−5 1.628 × 10−4 1.52 (1.25–1.84)
TT 19 2.5 18 1.2 0.020 NS 2.12 (1.11–4.07)
C 1240 81.8 2623 87.2 1.176 × 10−6 2.352 × 10−5 0.66 (0.56–0.78)
combined CC 753 65.5 1605 76.2 8.501 × 10−11 1.097 × 10−8 0.60 (0.51–0.70)
CT 366 31.9 470 22.3 2.532 × 10−9 3.266 × 10−7 1.63 (1.39–1.91)
TT 30 2.6 32 1.5 0.029 NS 1.74 (1.05–2.88)
C 1872 81.5 3680 87.3 1.766 × 10−10 7.594 × 10−9 0.64 (0.56–0.73)

Pc, Bonferroni corrected p value; NS, not significant; SNP, single nucleotide polymorphism.