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. 2016 Apr 25;6:24714. doi: 10.1038/srep24714

Figure 1. Running performance in female ApoE/LDLR−/− mice and C57BL6/J mice.

Figure 1

(A) Body mass, (B,C) whole body maximal oxygen consumption (V’O2max) during incremental test, (D) maximal velocity (vmax) and (E) maximal distance (DISTmax) in running incremental test in 3-month (3m) and 6–8-month (6-8m) old ApoE/LDLR−/− and C57BL6/J mice. Statistical analysis was performed using two-sided t-test or non-parametric Mann-Whitney test depending on the results of D’Agostino and Pearson omnibus normality test. *indicates statistically significant difference between C57BL6/J and ApoE/LDLR−/− mice, #indicates statistically significant age-dependent difference within the strain. *,#P < 0.05, ##P < 0.01, ***,###P < 0.001; n = 16–20 for 3-month old C57BL6/J mice, n = 16–19 for 3-month old ApoE/LDLR−/− mice, n = 9–11 for 6–8-month old C57BL6/J mice and n = 11 for 6–8-month old ApoE/LDLR−/− mice. Data are presented as the mean ± SEM.