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. 2016 Apr 25;6:24879. doi: 10.1038/srep24879

Table 5. Differences between male and female mice in the Light Dark Box test (arithmetic means ± SEM).

parameter   WT WTNH4Cl kl/klNH4Cl WTLVD kl/klLVD
time in hidden area [min] 8.67 ± 0.48 8.71 ± 0.29 6.26 ± 0.57 8.56 ± 0.38 8.47 ± 0.40
8.79 ± 0.23 8.37 ± 0.53 5.66 ± 0.67 8.91 ± 0.35 8.39 ± 0.32
ttest 0.8226 0.5645 0.5234 0.5208 0.8785
visits in light area 13.91 ± 3.69 15.75 ± 5.23 26.92 ± 3.69 11.67 ± 3.48 14.36 ± 3.92
17.10 ± 5.23 17.57 ± 5.75 32.88 ± 4.04 15.67 ± 6.56 15.40 ± 4.16
ttest 0.6217 0.8180 0.3000 0.6017 0.8579
number of rearings in light area 3.55 ± 1.06 3.63 ± 1.43 16.12 ± 3.32 3.50 ± 1.63 3.00 ± 0.62
4.27 ± 1.18 3.00 ± 1.07 13.54 ± 2.85 1.67 ± 0.72 3.10 ± 1.34
ttest 0.6516 0.7377 0.5747 0.3268 0.9449
rearing time light area [s] 8.69 ± 4.40 5.37 ± 2.14 33.31 ± 6.41 5.66 ± 2.86 4.34 ± 1.31
7.20 ± 2.33 8.51 ± 2.45 33.32 ± 11.67 6.06 ± 2.41 8.13 ± 2.86
ttest 0.7673 0.3493 0.9985 0.9166 0.2280
distance in light area [m] 2.51 ± 0.55 2.27 ± 0.77 8.870 ± 1.05 1.77 ± 0.57 1.90 ± 0.45
2.17 ± 0.39 2.33 ± 1.09 10.27 ± 1.58 2.33 ± 0.96 1.84 ± 0.40
ttest 0.6217 0.9659 0.4444 0.6257 0.9242
time in entrance area [min] 1.55 ± 0.93 3.46 ± 1.17 9.24 ± 1.31 1.39 ± 0.83 1.05 ± 0.75
1.99 ± 0.03 2.71 ± 1.32 8.25 ± 1.44 1.97 ± 1.66 0.57 ± 0.35
ttest 0.7532 0.6746 0.6248 0.5077 0.6521
number of rearings in hidden area 21.33 ± 6.29 20.38 ± 7.01 41.35 ± 5.39 16.67 ± 5.10 15.46 ± 5.42
19.82 ± 6.27 22.86 ± 9.45 41.52 ± 6.01 18.67 ± 10.27 14.00 ± 4.70
ttest 0.8665 0.8335 0.9444 0.8650 0.8430
rearing time hidden area [s] 5.51 ± 1.07 3.91 ± 1.50 11.19 ± 0.85 6.34 ± 1.82 5.24 ± 1.32
5.79 ± 1.42 4.41 ± 1.86 11.40 ± 1.07 6.11 ± 2.70 6.34 ± 1.59
ttest 0.7965 0.8361 0.8345 0.9474 0.5904
time in light area [min] 1.34 ± 0.48 1.29 ± 0.29 3.74 ± 0.57 1.44 ± 0.38 1.53 ± 0.40
1.22 ± 0.23 1.64 ± 0.53 4.34 ± 0,67 1.09 ± 0.35 1.62 ± 0.32
ttest 0.8226 0.5645 0.5234 0.5208 0.8785
speed [cm/s] 3.45 ± 0.43 2.41 ± 0.36 4.53 ± 0.38 2.95 ± 0.36 2.23 ± 0.36
2.40 ± 0.41 2.49 ± 0.33 4.39 ± 0.50 2.03 ± 0.34 2.52 ± 0.48
ttest 0.9335 0.8677 0.8353 0.0948 0.6244