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. 2016 Apr 20;7:11372. doi: 10.1038/ncomms11372

Table 1. Decomposition of G1 variability.

  G1 noise for λTG1 Noise due to size control Size-independent noise
WT (exp) 0.55 0.31 (32%) 0.45 (68%)
WT (sim) 0.52 0.23 (19%) 0.47 (81%)
6 × Cln3 (exp) 0.44 0.25 (32%) 0.36 (68%)
6 × Cln3 (sim) 0.33 0.13 (15%) 0.31 (85%)
6 × Cln2 (exp) 0.48 0.30 (39%) 0.37 (61%)
6 × Cln2 (sim) 0.43 0.25 (35%) 0.34 (65%)
6 × Cln3, 6 × Cln2 (exp) 0.37 0.18 (24%) 0.32 (76%)
6 × Cln3, 6 × Cln2 (sim) 0.40 0.10 (6%) 0.39 (94%)

WT, wild type.

Decomposition of G1 variability in terms of deterministic size control and a residual that is attributable to molecular noise under the assumption that λTG1 can be decomposed into the sum of a suitable deterministic function of the initial protein content f(P(0)) plus a stochastic variable. The chosen function for f(P(0)) is the hyperbola described in Fig. 3e. The experimental data are from ref. 13.