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. 2012 Dec 12;25(2):716–727. doi: 10.1177/0962280212465498

Table 6.

Error rates when treatment is added at interim, adjusting the upper boundary at the second stage. Based on 100,000 simulations

Design u2adj α+ 1-β+ 1-β+*
OBF 2.245 0.051 0.893 0.862
P 2.455 0.051 0.894 0.730
T 2.384 0.051 0.892 0.755