(A) Body weight of Sirt5 WT and KO male mice (n = 4–5 per genotype, 8-wk-old males). (B) Left ventricular internal dimension in systole (LVIDs), (C) left ventricular internal dimension in diastole (LVIDd), (D) volume in systole, (E) volume in systole, (F) posterior wall thickness, and (G) stroke volume did not altered significantly in Sirt5 KO male mice. All graphs are shown as mean ± SEM.