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. Author manuscript; available in PMC: 2016 Apr 25.
Published in final edited form as: Am J Ind Med. 2014 Oct 28;58(1):101–111. doi: 10.1002/ajim.22393

TABLE III.

Selection of Observed Asthmagens in Products Used by Participants and the Corresponding Usage in the Healthcare Setting

Asthmagens Chemical group In products used by
Methacrylatesa Acrylate Dental and clinical laboratory technicians during laboratory procedures; dental
assistants when performing procedures on patients
Acrylatesb Acrylate Dental laboratory technicians during laboratory procedures
Quaternary ammonium compoundsc Quats Dental assistants and laboratory technicians, registered nurses, licensed practical
nurses, certified nursing assistants, endoscopy technicians, medical equipment
preparers, floor strippers /waxers, and housekeepers for general cleaning of
surfaces, furniture, and equipment
Ethanolaminesd Amine Certified nursing assistants, endoscopy technicians, medical equipment preparers, for
instrument cleaning; floor strippers/waxers and housekeepers for general cleaning
of surface, furniture, and equipment
Acidse Carboxylic acid Acid oxidizer Registered and licensed practical nurses when working in dialysis units; registered
and licensed practical nurses, dental assistants, endoscopy technicians, and
medical equipment preparers for cleaning, sterilizing, and high-level disinfecting
medical instruments
Aluminum oxide Metal Dental laboratory technicians during laboratory procedures
Ammonium hydroxide Base Housekeepers for general cleaning of surfaces
Ethylene oxide Ether Medical equipment prepares when sterilizing and high-level disinfecting medical
instruments
Eugenol Other Dental assistants when performing procedures on patients
Formaldehyde Aldehyde Clinical laboratory technicians during laboratory procedures
Ortho-phthalaldehydef Aldehyde Licensed practical nurses and endoscopy technicians for cleaning, sterilizing, and
high-level disinfecting medical instruments
Subtilisin Enzyme Licensed practical nurses, endoscopy technicians and medical equipment preparers
for cleaning instruments
Sodium hypochzlorite Oxidizer Registered and licensed practical nurses, respiratory therapists, clinical laboratory
technicians, and housekeepers for general surface cleaning
Ammonia Ammonia Floor strippers/waxers for stripping and finishing floors

Note: Classification as asthmagen based on Asthma in the Workplace 3rd Edition [Bernstein et al., 2006] and the Association of Occupational and Environmental Clinics Exposure Code Lookup webpage [AOEC, 2012] unless otherwise noted. Product usage based on field observations during data collection and information from manufacturers and material safety data sheets.

a

Includes 2-(acetoacetoxy) ethyl methacrylate, methyl methacrylate, poly methyl methacrylate.

b

Includes ethyl cyanoacrylate, ethyl-2 cyanoacrylate.

c

Includes alkyl (60% C14, 30% C16, 5% C12, 5% C18) dimethyl benzyl ammonium chloride, alkyl (68% C12, 32% C14) dimethyl ethylbenzyl ammonium chloride, benzyl-C12-16 alkyl dimethyl ammonium chloride, didecyl dimethyl ammonium chloride, dioctyl dimethyl ammonium chloride, N-alkyl (C14 50%, C12 40%, C16 10%) dimethyl benzyl ammonium chloride, octyldecyldimethylammonium chloride, quaternary ammonium chloride.

d

Includes monoethanolamine, triethanolamine.

e

Includes acetic acid, hydrochloric acid, sulfuric acid.

f

Classification as a sensitizer based on evidence from other literature [Anderson et al., 2010].