Table 4.
Hospital Costs and Clinical Outcomes Between Transradial and Transfemoral Intervention: Subgroup Analyses by Acute Myocardial Infarction, Acute Coronary Syndrome, and Stable Angina
| Transradial Intervention (95% CI) | Transfemoral Intervention (95% CI) | Unadjusted Difference (95% CI) | Adjusted Difference (95% CI) | P Value | |
|---|---|---|---|---|---|
| Acute myocardial infarction | n=992 | n=102 | |||
| Total costs, ¥ | 59 858 (57 120–62 728) | 72 308 (67 466–77 498) | −12 450 (−15 777 to −8927) | −8147 (−11 401 to −4708) | <0.001 |
| Length of stay, day | 7.5 (6.9–8.0) | 9.8 (8.5–11.2) | −2.3 (−3.1 to −1.5) | −1.3 (−2.1 to −0.3) | 0.01 |
| Major adverse cardiac events† | 18 (1.8) | 3 (2.9) | 0.61 (0.26–1.42)a | 0.87 (0.36–2.09)a | 0.75 |
| BARC ≥2 | 62 (6.3) | 19 (18.6) | 0.29 (0.17–0.51)a | 0.33 (0.17–0.63)a | <0.001 |
| BARC ≥3 | 12 (1.2) | 3 (2.9) | 0.40 (0.15–1.09)a | 0.57 (0.20–1.60)a | 0.28 |
| Acute coronary syndrome | n=3260 | n=409 | |||
| Total costs, ¥ | 57 585 (54 779–60 534) | 67 246 (63 082–71 684) | −9661 (−11 531 to −7727) | −8197 (−10 795 to −5477) | <0.001 |
| Length of stay, day | 6.3 (5.8–6.8) | 8.7 (7.7–9.9) | −2.4 (−2.9 to −1.9) | −1.8 (−2.3 to −1.4) | <0.001 |
| Major adverse cardiac events† | 61 (1.9) | 17 (4.2) | 0.44 (0.28–0.70)a | 0.50 (0.35–0.71)a | <0.001 |
| BARC ≥2 | 176 (5.4) | 47 (11.5) | 0.44 (0.34–0.56)a | 0.44 (0.34–0.58)a | <0.001 |
| BARC ≥3 | 24 (0.7) | 8 (2.0) | 0.37 (0.20–0.71)a | 0.38 (0.19–0.76)a | 0.007 |
| Stable angina | n=1264 | n=173 | |||
| Total costs, ¥ | 58 682 (54 962–62 654) | 66 746 (60 536–73 593) | −8064 (−11 575 to −4329) | −4829 (−8249 to −1200) | 0.01 |
| Length of stay, day | 5.9 (5.2–6.5) | 8.0 (6.9–9.1) | −2.1 (−2.6 to −1.6) | −1.2 (−1.7 to −0.7) | <0.001 |
| Major adverse cardiac events† | 20 (1.6) | 6 (3.5) | 0.45 (0.26–0.77)a | 0.62 (0.36–1.08)a | 0.09 |
| BARC ≥2 | 67 (5.3) | 20 (11.6) | 0.43 (0.17–1.06)a | 0.42 (0.13–1.41)a | 0.16 |
| BARC ≥3 | 5 (0.4) | 4 (2.3) | 0.17 (0.06–0.47)a | 0.29 (0.09–0.91)a | 0.03 |
One US dollar is approximately equivalent to 6.3 Chinese yuan. BARC indicates Bleeding Academic Research Consortium.†Composite of death, myocardial infarction, revascularization, or BARC ≥3 bleeding.
a
Odds ratio.