Table 3.

Time of Clinically Significant AF Episode (Requiring Hospitalization or Medical Treatment) by Trimester of Onset

	No. of Cases (n=60)	Rate Per 100 000 Pregnancies (95% CI)	OR (95% CI)	P Value
First trimester	9	3.4 (1.2–5.6)	1
Second trimester	18	6.8 (3.7–9.9)	2.0 (0.9–5.1)	0.12
Third trimester	29	11.0 (7.0–15.0)	3.2 (1.5–7.7)	0.002
Postpartum (6 months)	4	1.5 (0.03–3.0)	0.4 (0.1–1.6)	0.26

P value: 2‐sided P value calculated using Fisher's exact test. P<0.05 was considered statistically significant. Rates per 100 000 were unadjusted rates. AF indicates atrial fibrillation or atrial flutter; OR, odds ratio.