Table 2.
Patients treated with curative intent for radiation-induced sarcoma (RIS)
| No. | Sex | Age at primary RT (yr) | Primary tumor | Duration to RIS (yr) | RIS histology | Initial RT dose (cGy) | RIS treatment | RM | Disease status | Survival status at last follow-up |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | F | 34 | Breast ca. | 9.7 | OSA | 6,040 | RT+CTx+Op+CTx | R0 | NED with 10 yr survival | Death |
| 2 | F | 44 | Breast ca. | 5.7 | Angiosarcoma | 6,100 | Op+CTx | R0 | LR after 10 mo | Alive |
| 3 | F | 51 | Breast ca. | 7.7 | Angiosarcoma | 5,940 | 〇p | R0 | LR after 4 mo | Death |
| 4 | F | 30 | Breast ca. | 13.1 | OSA | 4,680 | Op | R1 | LR after 6 mo | Death |
| 5 | F | 40 | Breast ca. | 8.2 | Chondrosarcoma | 6,600 | Op | R0 | LR after 3 mo and DM after 3 mo | Alive |
| 6 | F | 48 | Breast ca. | 4.8 | MFH | 5,040 | Op | R0 | LR after 13 mo and DM after 13 mo | Alive |
| 7 | F | 45 | Cervical ca. | 26.9 | OSA | 5,040 | Op+CTx | R0 | NED | Alive |
| 8 | F | 40 | Cervical ca. | 14.9 | OSA | 5,040 | CTx+Op | R0 | NED | Alive |
| 9 | F | 49 | Cervical ca. | 13.2 | MFH | 6,040+ICR | RT+Op | R0 | LR after 15 mo | Alive |
| 10 | F | 52 | Cervical ca. | 6.7 | Myxoid liposarcoma | 5,040+ICR | 〇p | R0 | LR after 12 mo | Alive |
| 11 | F | 44 | Cervical ca. | 17.6 | MFH | 5,040 | CTx+Op | R0 | DM after 15 mo | Alive |
| 12 | F | 67 | Rectal ca. | 8.4 | MFH | 5,400 | 〇p | R0 | NED with wound complication | Death |
| 13 | M | 55 | Rectal ca. | 13.3 | OSA | 5,040 | Op+CTx | R0 | DM after 10 mo | Death |
| 14 | M | 37 | Rectal ca. | 26 | MFH | 5,040 | Op | R0 | LR after 21 mo and DM after 29 mo | Death |
| 15 | M | 17 | Nasopharynx ca. | 14.6 | OSA | 7,020 | Op+CTx | R0 | NED | Alive |
| 16 | F | 53 | Nasopharynx ca. (ACC) | 10.2 | OSA | 6,000 | Op+CTx | R0 | LR after 14 mo and DM after 24 mo | Alive |
| 17 | F | 41 | Craniopharyngioma | 13.2 | MFH | 5,440 | CTx+Op | R0 | NED with 10 yr survival | Death |
| 18 | M | 53 | Parotid ca. (ACC) | 10.8 | MFH | 7,040 | Op+RT | R0 | DM after 10 mo | Alive |
| 19 | F | 50 | Lymphoma (DLBC, trunk) | 1.9 | Fibromyxoid sarcoma | 3,000 | 〇p | R0 | NED | Alive |
RT, radiotherapy; RM, resection margin; F, female; ca., cancer; OSA, osteosarcoma; CTx, chemotherapy; Op, operation; NED, no evidence of disease; LR, local recurrence; DM, distant metastasis; MFH, malignant histiocytoma; ICR, intracavitary radiotherapy; M, male; ACC, adenoid cystic carcinoma; DLBC, diffuse large B cell.