Table 2.
Comparison analyses of volumetric parameters according to recurrence status
| Parameter | Recurrence, mean (range, cm3) |
p-valuea) | |
|---|---|---|---|
| No | Yes | ||
| Pre-RT GTV | |||
| Primary | 24.2 (1.5 to 93.8) | 32.6 (2.9 to 165.7) | 0.089 |
| Nodal | 16.8 (0.0 to 112.7) | 26.2 (0.0 to 116.6) | 0.022 |
| Total | 40.9 (1.5 to 138.0) | 58.8 (6.0 to 185.3) | 0.004 |
| Mid-RT GTV | |||
| Primary | 14.5 (0.6 to 74.2) | 23.4 (1.6 to 104.5) | 0.006 |
| Nodal | 7.9 (0.0 to 49.8) | 14.7 (0.0 to 84.9) | 0.009 |
| Total | 22.3 (1.0 to 87.9) | 38.0 (5.3 to 113.8) | < 0.001 |
| TVRRb) | |||
| Primary | -43.4 (-93.5 to 3.8) | -28.1 (-86.9 to 51.5) | 0.004 |
| Nodalc) | -46.1 (-85.5 to 98.9) | -38.4 (-83.0 to 139.3) | 0.143 |
| Total | -44.3 (-87.2 to 3.80) | -34.0 (-72.0 to 78.3) | 0.004 |
RT, radiation therapy; GTV, gross tumor volume, TVRR, tumor volume reduction rate.
a)
Calculated by Mann-Whitney test,
b)
Tumor volume reduction rate=(Mid-RT GTV–Pre-RT GTV)/Pre-RT GTV,
c)
Nodal TVRRs were calculated from 130 patients with clinically positive nodes.