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. Author manuscript; available in PMC: 2016 Apr 25.
Published in final edited form as: ACS Chem Biol. 2015 Jan 28;10(4):1082–1093. doi: 10.1021/cb500759p

Table 3.

Release of Hemoglobin, ATP, and miRNA from Red Blood Cells in the Presence of PSPF Peptides

peptide RBC lysis assay (% relative to Triton X-100 controls)
hemoglobin release
% ATP at 5 μM
% miRNA at 5 μM
pH 7.5 pH 5.4 pH 7.5 pH 5.4 pH 7.5 pH 5.4
PSPF-DQA none none 3.81 17.91 0.81 18.61
PSPF-DQG none none 3.21 8.61 0.06 0.16
PSPF-DKA none none 4.64 5.79 4.13 0.79
PSPF-DKG none none 7.54 24.1 5.54 7.47
PSPF-EQA none none 3.69 3.61 0.46 0.02
PSPF-EQG none none 3.36 9.52 0.15 2.64
PSPF-EKA none none 2.02 3.66 0.51 0.21
PSPF-EKG none none 3.38 27.3 0.14 12.54
PSPF-HQA none none 6.17 11.72 0.02 1.43
PSPF-HQG none none 5.69 10.55 0.2 0.64
PSPF-HKA none none 0.93 5.7 0.43 0.02
PSPF-HKG none none 32.1 39.22 72.28 0.44