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. 2015 Feb 3;2(1):51–52. doi: 10.4161/23328940.2014.992657

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© 2015 The Author(s). Published with license by Taylor & Francis Group, LLC

This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.

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Figure 1. — Schematic of the current theory on how hypoxia/ischemia facilitates cell death in the brain. Yacobi et al.¹ demonstrated that long-term heat acclimation can reduce glutamate-mediated calcium influx and improve outcomes following hypoxic injury by altering the expression of NMDA and AMPA receptor subunits.