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. Author manuscript; available in PMC: 2016 Apr 25.
Published in final edited form as: Prog Mol Biol Transl Sci. 2013;117:187–205. doi: 10.1016/B978-0-12-386931-9.00008-8

Figure 8.1.

Figure 8.1

Schematic model of functional responses induced by GPCR homomers as compared to GPCR heteromers. Combinations of drugs modulate different patterns of signaling responses, and a cross talk between the components of the GPCR heteromeric complex leads to unique signaling properties.