Table 1.
Estimated risk of hepatic steatosis (hepatic TG content > 5.5%) in 2736 participants of the Dallas Heart Study per minor (T) allele of MBOAT7/TMC4 rs641738 C>T.
| Ethnic | Hepatic steatosis |
||
|---|---|---|---|
| Group | OR | 95% CI | P-value |
| All | 1.20 | 1.05 - 1.37 | 0.006 |
| African American | 1.17 | 0.97 - 1.43 | 0.110 |
| European American | 1.37 | 1.09 - 1.72 | 0.007 |
| Hispanic American | 0.99 | 0.72 - 1.37 | 0.97 |
OR: odds ratio; CI: confidence interval
Odds ratios and confidence intervals were computed using logistic regression models, assuming an additive effect of rs641738 (by coding the genotypes 0, 1, 2 for CC, CT, and TT, respectively) adjusted for ethnicity, age, gender, BMI, IFG/T2DM, PNPLA3 I148M and TM6SF2 E167K genotypes.