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. 2016 Apr 25;11(4):e0153807. doi: 10.1371/journal.pone.0153807

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© 2016 Fahlenkamp et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 1 — A simplified sketch of the study procedure is shown in Fig 1. After obtaining written informed consent and baseline examination, patients were first randomized to receive xenon or sevoflurane anesthesia for their individually scheduled surgery, then randomized to receive dexamethasone or placebo for prophylaxis of post-operative nausea. Within the first hour of anesthesia, the randomized prophylactic treatment was applied. Patients were monitored for 24h following anesthesia in fixed intervals (during PACU stay at 0, 5, 15, 30, 45, 60, 75, 105, 120 min until discharge as well as 2h, 6h, and 24h post anesthesia). The study-specific survey was completed 24h post anesthesia.