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. 2016 Apr 25;11(4):e0153505. doi: 10.1371/journal.pone.0153505

Fig 1. Effect of rapamycin and CQ on sevoflurane-induced memory impairment.

Fig 1

(A) Escape latency (time to find the hidden platform) plotted against training day. Repeated measures ANOVA followed by a post hoc Bonferroni multiple comparison test: CON vs. SEV, P = 0.0002, F = 15.47, n = 9; SEV vs. SEV+RAP, P = 0.0155, F = 6.19, n = 9; SEV vs. SEV+CQ, P = 0.0412, F = 4.55, n = 9; CON vs. RAP, P = 0.0569, F = 0.33, n = 9; CON vs. CQ, P = 0.21, F = 15.47, n = 9. (B) The platform crossing times during the probe trial of the MWM test. (C) The time spent in the target quadrant during the probe test of MWM. Data are presented as mean ± SEM (n = 9). *P < 0.05, **P < 0.01, #P > 0.05.