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. 2016 Apr 25;11(4):e0154143. doi: 10.1371/journal.pone.0154143

Table 2. Clinical characteristics of severe TBE.

MER ME
Parameters n = 16 n = 34 P-value
DisabilitymRS, median (min.-max)
admission 5 (4–5) 4 (2–5) <0.001
> 12 month 4 (1–6) 1 (0–3) <0.0001
Intensive Care n (%) 14 (87.5%) 13 (38.2%) 0.004
Mechanical ventilation 8 (50%) 1 (2.9%) <0.001
Tracheotomy 3 (18.8%) 1 (2.9%) n.s.
Co-morbidity n (%)
Diabetes mellitus 7 (43.8%) 4 (11.8%) 0.024
Polyneuropathy 4 (25.0%) 0 (0.0%) 0.008
Alcohol consumption 5 (31.2%) 5 (14.7%) n.s.
others 3 (18.8%) 3 (8.8%) n.s.
Neuroimaging n (%)
Pathological MRI# findings 7 (58.3%) 4 (17.4%) 0.016

MER, meningoencephaloradiculitis; ME, meningoendephalitis; mRS, modified RANKIN scale [12].

Statistic was calculated with Mann-Whitney U-test† and with Fisher exact test‡, respectively.

#MRI was not available in all patients.