Table 4. SOX10 reactivity over time in nine patients during treatment follow up.

DERMA and METRIC study treatment regimens are described under Methods.

Patient No.	Treatment	Clinic	SOX10 reactivity	No samples
1	DERMA	No recurrence	positive initially at first treatment dose, then negative during treatment	7
2	Vemurafenib	Regression	negative	3
3	DERMA	Lymph met	negative	3
4	METRIC	Regression	Initially negative, then positive. Recurrence 2 months later	2
5	DERMA	Recurrence	Initially negative, positive 10 months before recurrence. Develops vitiligo.	5
6	Post surgery	Regression	initially positive SOX10, then negative with lung hilus tumor regression	5
7	METRIC	Regression	positive, progress 2 months later	1
8	DERMA	No recurrence	negative	2
9	METRIC	Regression	negative	3