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| HRM | RT-ASA | IdyllaTM | IHC | |
|---|---|---|---|---|
| Sensitivity | 87.1% | 93.5% | 93.5% | 81.7% |
| Specificity | 96.4% | 100.0% | 100.0% | 100.0% |
| PPV | 96.4% | 100.0% | 100.0% | 100.0% |
| NPV | 87.1% | 93.3% | 93.3% | 87.5% |
Abbreviations: IHC, immunohistochemistry; NGS, next-generation sequencing; HRM: High Resolution Melting; RT-ASA: Real-Time Allele Specific Amplification; NPV, negative predictive value; PPV, positive predictive value.
