Table 6. Gene-Environment Interaction Models of Tobacco and Alcohol Co-use.
Any Co-Use | Baseline | + School & Demographic Controls | + Psychological Controls | |||
---|---|---|---|---|---|---|
All | Sibling FE | All | Sibling FE | All | Sibling FE | |
EP | 1.096* | -- | 0.998 | -- | 1.011 | -- |
5HTTLPR*S′ | 0.936 | 2.039 | 0.915 | 2.039 | 1.017 | 1.994 |
EP × 5HTTLPR*S′ | 1.007 | 0.931 | 1.010 | 0.931 | 0.999 | 0.931 |
Prop Co-Use (PC) | 1.038* | -- | 0.988 | -- | 0.994 | -- |
5HTTLPR*S′ | 0.774* | 0.663 | 0.748* | 0.664 | 0.807* | 0.612 |
PC × 5HTTLPR*S′ | 1.009* | 1.013 | 1.010* | 1.013 | 1.008* | 1.015 |
| ||||||
Heavy Co-Use | Baseline | + School & Demographic Controls | + Psychological Controls | |||
All | Sibling FE | All | Sibling FE | All | Sibling FE | |
| ||||||
EP | 1.306* | -- | 1.033 | -- | 1.056 | -- |
5HTTLPR*S′ | 0.813* | 1.907 | 0.829+ | 1.875 | 0.878 | 1.997 |
EP × 5HTTLPR*S′ | 1.050+ | 0.802 | 1.051+ | 0.795 | 1.034 | 0.786 |
Prop Co-Use (PC) | 1.182* | -- | 1.019 | -- | 1.057 | -- |
5HTTLPR*S′ | 0.773* | 1.588 | 0.784* | 1.529 | 0.878 | 1.493 |
PC × 5HTTLPR*S′ | 1.047* | 0.901 | 1.048* | 0.900 | 1.034 | 0.910 |
Note:
: p<.05;
+: p<0.10.
Two-tailed tests are used for all coefficients except interactions, which are one-tailed tests.