. Author manuscript; available in PMC: 2017 May 1.

Published in final edited form as: Int J Radiat Oncol Biol Phys. 2016 Feb 16;95(1):279–286. doi: 10.1016/j.ijrobp.2016.02.032

Table 2.

Sensitivity analysis of the mean ratio of risk <R_c/R_p> to plausible variation in model parameters. Parameters varied with respect to the reference case (Ref.) are indicated in the leftmost column. SE indicates standard error. Sig. indicates whether a ratio of risk was significantly different than 1.

Variables	Model	α (Gy⁻¹)	μ_x/ν_x (Gy)	ν _i	k_c (μm/keV)	κ	<R_c/R_p>	SE	Sig.	p
Ref.	Full	0.067	3	ν _x	0.09	5	0.75	0.07	no	0.180
κ	Full	0.067	3	ν _x	0.09	1	0.92	0.08	no	0.180
κ	Full	0.067	3	ν _x	0.09	10	0.62	0.06	yes	0.004
k_c	Full	0.067	3	ν _x	0.01	5	0.51	0.05	yes	0.004
	Full	0.067	3	ν _x	0.19	5	0.85	0.08	no	0.180
	Full	0.067	3	ν _x	0.49	5	0.87	0.08	no	0.180
μ_x/ν_x	Full	0.067	1	ν _x	0.09	5	0.69	0.06	yes	0.004
μ_x/ν_x	Full	0.067	5	ν _x	0.09	5	0.76	0.07	no	0.180
α	Full	0.01	3	ν _x	0.09	5	0.68	0.05	yes	0.004
α	Full	0.1	3	ν _x	0.09	5	0.74	0.08	no	0.180
ν _i	Full	0.067	3	0	0.09	5	0.80	0.07	no	0.180
k_c and κ	Simple	0.067	-	ν _x	0.01	1	0.55	0.05	yes	0.004
	Simple	0.067	-	ν _x	0.09	1	1.18	0.11	yes	0.039
	Simple	0.067	-	ν _x	0.19	1	1.87	0.17	yes	0.039
	Simple	0.067	-	ν _x	0.49	1	3.31	0.30	yes	0.004
	Simple	0.067	-	ν _x	0.01	5	0.52	0.05	yes	0.004
	Simple	0.067	-	ν _x	0.09	5	0.88	0.08	no	0.180
	Simple	0.067	-	ν _x	0.19	5	1.10	0.11	no	0.508
	Simple	0.067	-	ν _x	0.49	5	1.38	0.14	yes	0.039
	Simple	0.067	-	ν _x	0.01	10	0.50	0.05	yes	0.004
	Simple	0.067	-	ν _x	0.09	10	0.66	0.06	yes	0.039
	Simple	0.067	-	ν _x	0.19	10	0.73	0.07	yes	0.039
	Simple	0.067	-	ν _x	0.49	10	0.80	0.08	no	0.180