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Individual and combined effect of LRIG1 loss and hypermethylation on clinical outcome. Kaplan-Meier curves of progression free survival for cervical cancer patients (cohort 1) with and without loss of LRIG1 (A), with and without hypermethylation of LRIG1 (B), the 2 combined (C), and high and low LRIG1 expression (D). P-values in log-rank test and number of patients are indicated. NL: no loss; L: loss; NM: not hypermethylated; M: hypermethylated.
