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. Author manuscript; available in PMC: 2016 Apr 25.
Published in final edited form as: Breast Cancer Res Treat. 2013 Oct 25;142(1):45–57. doi: 10.1007/s10549-013-2733-5

Figure 5. NKT cells may rescue reprogrammed PBMCs from MDSC suppression via an NKG2D-dependent pathway.

Figure 5

PBMCs were either maintained in IL-2 for six days (IL-2) or were reprogrammed with B/I and γ-c cytokines (Reprogrammed) and subsequently analyzed for NKG2D expression in CD161+ NKT cells (A) or CD56+ NKT cells (B) using flow cytometry (n=5). Data represent Mean ± SEM. C) Reprogrammed PBMCs were cultured in the presence of HER-2/neu ICD pulsed DCs with or without sorted MDSCs and anti-NKG2D blocking antibody (n=3). Data represent Least Squares Means ± SEM.