Table 2.
Prevalence of SDB and asthma as a risk factor
| Author (year) | Country | N | Male | Mean age (years) | Asthma diagnosis | SDB diagnosis | SDB prevalence (%) – asthma vs controls | OR (95% CI) |
|---|---|---|---|---|---|---|---|---|
| Redline et al (1999)41 | USA | 399 | 194 | 10.9 | History + spirometry | PSG AHI>10 | 11.8 vs 28 | 3.83 (1.39–10.55) |
| Corbo et al (2001)15 | Italy | 2,209 | 722 | 12.5 | Previous diagnosis or questionnaire | Snoring “often” | 12.2 vs 7.6 | 1.79 (0.97–3.33) |
| Chng et al (2004)14 | Singapore | 11,114 | 5,212 | 5.8 | Questionnaire | Snoring for > 3 nights/week | 8.6 vs 5.1 | 1.83 (1.50–2.24) |
| Urschitz (2004)26 | Germany | 1,144 | 585 | 9.6 | History | “Frequently” or “always” snoring | 7.1 vs 9.8 | 0.68 (0.24–1.94) |
| Ersu et al (2004)17 | Turkey | 2,147 | 1,074 | 8.5 | History, questionnaire | “Often” or “always” snoring | 9.1 vs 7.6 | 1.25 (0.75–2.09) |
| Bidad et al (2006)13 | Iran | 2,900 | 1,200 | 14 | ISAAC questions | Snoring for ≥ 3 nights/week | 10.7 vs 7.1 | 1.64 (1.05–2.58) |
| Marshall et al (2007)22 | USA | 219 | 107 | 5 | ISAAC questions, spirometry | Snoring for ≥ 3 nights/week | 29.1 vs 16.9 | 2.71 (1.42–5.16) |
| Li et al (2010)20 | People’s Republic of China | 20,152 | 9,890 | 9 | Previous diagnosis | “Frequently” or “almost always” snoring | 17.8 vs 10.5 | 2.09 (1.72–2.54) |
| Kheirandish-Gozal et al (2011)40 | USA | 92 | 49 | 6.6 | History | PSG AHI 5/hour TST | 63.0 vs 4.0 | 40.9 (12.9–144.1) |
| Fadzil et al (2012)18 | Malaysia | 550 | 285 | 8.5 | Questionnaire | PSQ >0.33 | 29.2 vs 13.5 | 2.62 (1.34–5.15) |
| Ng et al (2014)33 | People’s Republic of China | 2,005 | 1,173 | 15.3 | Questionnaire | Snoring for ≥ 6 nights/week | 17.9 vs 9.7 | 2.18 (1.25–3.71) |
Abbreviations: SDB, sleep-disordered breathing; OR, odds ratio; CI, confidence interval; PSG, polysomnography; AHI, apnea–hypopnea index; ISAAC, International Study on Asthma and Allergies in Childhood; TST, total sleep time; PSQ, Pediatric Sleep Questionnaire.