Table 1.

Quality assessment of included sutdies.

Author, year	Q1	Q2	Q3	Q4	Q5	Q6	Q7	Q8	Q9	Q10	Q11	Q12	Q13	Q14	QUADAS score
	Spectrum composition	Selection criteria	Appropriate reference standard	Disease progression bias	Partial verification bias	Differential verification bias	Incorporation bias	Test execution details	Reference execution details	Test review bias	Diagnostic review bias	Clinical review bias	Intermediate results	Withdrawals
Beland et al., 2014	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	14
Ferraioli et al., 2012	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	14
Zeng et al., 2014	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	14
Yoon et al., 2014	Yes	Yes	Yes	Unclear	Yes	Yes	Yes	Yes	Yes	Unclear	Yes	Yes	Yes	Yes	12
Jeong et al., 2014	Yes	Yes	Yes	Unclear	Yes	Yes	Yes	Yes	Yes	Yes	Unclear	Yes	Yes	Yes	12
Samir et al., 2014	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	14
Zheng et al., 2015	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	14
Tada et al., 2015	Yes	Yes	Yes	Unclear	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	13