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. Author manuscript; available in PMC: 2016 Nov 1.
Published in final edited form as: J Neurochem. 2015 Sep 3;135(3):445–452. doi: 10.1111/jnc.13239

Figure 1. tMCAO affects gene expression of both pro- and anti-inflammatory genes and chemokine accumulation.

Figure 1

A. The presence of spectrin cleavage in injured (I) regions as compared to naïve (N) or contralateral (C) regions was used to select injured mice. B. Representative RT-PCR examples of pro- and anti-inflammatory genes in whole tissue lysates. C. Fold increase in the levels of individual chemokines 24 hours after reperfusion. Significance is shown for CD36ko Vs. WT. N – naïve, C – contralateral, I – injured. C. Representative examples of superoxide accumulation (DHE, Red) in WT (top) and CD36ko (bottom) 24 hours after reperfusion. Yellow arrows point at DHE+ cells. No significant increase in superoxide accumulation is seen in Iba1+ cells (green).