Table 1.
Cell characteristics of layer V pyramidal neurons of rats trained in the RI task and behavioral controls
Training group | Number of subjects | Number of cells | AMPA/NMDA | Series resistance (MΩ) | Input resistance (MΩ) | Membrane capacitance (pF) | Holding current (pA) |
---|---|---|---|---|---|---|---|
Prelimbic | |||||||
RI task | 6 | 16 | 1.21 ± 0.09 | 7.1 ± 0.6 | 53.0 ± 3.5 | 45.2 ± 2.4 | 655.0 ± 38.8 |
Operant control | 5 | 15 | 0.70 ± 0.08 | 6.3 ± 0.7 | 52.5 ± 6.0 | 53.4 ± 3.6 | 638.8 ± 85.9 |
Yoked control | 4 | 12 | 0.76 ± 0.07 | 6.9 ± 0.8 | 55.4 ± 5.9 | 49.8 ± 4.2 | 637.1 ± 68.1 |
Weight control | 5 | 11 | 0.72 ± 0.07 | 5.4 ± 0.5 | 48.2 ± 3.9 | 59.9 ± 8.3 | 595.1 ± 52.1 |
Age control | 6 | 16 | 0.69 ± 0.05 | 5.4 ± 0.2 | 55.0 ± 6.0 | 54.5 ± 2.4 | 605.1 ± 67.0 |
Infralimbic | |||||||
RI task | 5 | 11 | 0.74 ± 0.09 | 6.6 ± 0.7 | 72.1 ± 11.0 | 48.1 ± 6.3 | 537.9 ± 70.8 |
Operant control | 5 | 13 | 0.75 ± 0.06 | 8.3 ± 1.3 | 73.1 ± 7.6 | 41.3 ± 3.6 | 449.8 ± 39.7 |
Yoked control | 4 | 7 | 0.76 ± 0.10 | 8.2 ± 1.1 | 101.5 ± 7.7 | 43.7 ± 5.5 | 366.4 ± 89.2 |
Weight control | 4 | 10 | 0.83 ± 0.08 | 6.6 ± 0.6 | 61.6 ± 6.6 | 45.1 ± 2.4 | 550.9 ± 117.9 |
Age control | 4 | 12 | 0.75 ± 0.07 | 5.5 ± 0.2 | 48.1 ± 3.5 | 48.1 ± 3.5 | 579.3 ± 90.2 |
Values were obtained with a 10 ms, +10 mV pulse while holding neurons at +40 mV. No significant differences between experimental groups were observed for any variable, with the exception of AMPA/NMDA (bolded).