Kaplan-Meier curves for time to menopause in single nucleotide
polymorphism (SNP) carriers by baseline smoking behavior. A: Median
time from study entry to menopause in CYP3A4*1B carriers
reporting smoking at baseline, 11.36 years. Median time from study entry to
menopause in CYP3A4*1B carriers reporting no smoking at
baseline, 13.91 years. Solid line, survival curve in carriers who smoke; dashed
line, survival curve in carriers who do not smoke. B: Median time
from study entry to menopause in CYP1B1*3 carriers reporting
smoking at baseline, 10.42 years. Median time from study entry to menopause in
CYP1B1*3 carriers reporting no smoking at baseline, 11.36
years. Solid line, survival curve in carriers who smoke; dashed line, survival
curve in carriers who do not smoke. EA, European American.