FIGURE 5.

The pathway leading from geraniol to secologanin in C. roseus. CYP76B6: Geraniol 8-oxidase (Collu et al., 2001; Höfer et al., 2013; Miettinen et al., 2014), 8-HGO: 8-hydroxygeraniol oxidoreductase (Miettinen et al., 2014), IS: iridoid synthase (Geu-Flores et al., 2012). 7DLGT: 7-deoxyloganetic acid glycosyltransferase (Asada et al., 2013; Miettinen et al., 2014), LAMT: loganic acid methyltransferase (Madyastha et al., 1973; Murata et al., 2008), CYP72A1: secologanine synthase (Irmler et al., 2000), SLS2, secologanine synthase 2 (de Bernonville et al., 2015). Glc, (β-D)-glucopyranosyl moiety.