Table 1.

Redox components alteration in various glioblastoma cell lines.

Organelle	Antioxidant present	Reactive specie produced in normal conditions
Mitochondria	MnSOD	${\text{O}}_2^{•-}$, H2O2, O2, OH⋅
	Glutathione peroxidase
	Glutathione reductase
	Catalase
	Quinones (coenzymes Q)
	GSH
	NADH
	Thioredoxin
ER	Glutathion (GSH)	O2, H2O2, OH⋅
	Cu/Zn-superoxide
	Thioredoxin
	Glutaredoxin
	Peroxiredoxin
	Endoplasmic reticulum oxidase
	Protein disulfide isomerase
	Quinones (coenzymes Q)
Golgi	Quinones (coenzymes Q)	${\text{O}}_2^{•-}$, H2O2, OH⋅
	Cu, Zn-SOD
	Transferrine
Peroxisomes	Catalase	${\text{O}}_2^{•-}$, H2O2
	NADH
	FAD
	Cytochrome b
	Ubiquinone
Cytosol	Cu/Zn-SOD	${\text{O}}_2^{•-}$, H2O2, OH⋅, O2
	Protein disulfide isomerase
Chloroplast	Protein disulfide isomerase	${\text{O}}_2^{•-}$, H2O2, OH⋅
	Quinones (coenzymes Q)
Nucleus	Glutathione and thioredoxin	${\text{O}}_2^{•-}$, H2O2, OH⋅