Table 1.

Clinico-pathological characteristics of 86 breast cancer patients

Characteristics	Value (%)
Age (years)
<50	32 (37.2)
>50	54 (62.8)
Menopausal status
Premenopausal	29 (33.7)
Postmenopausal	57 (66.3)
Tumor size (cm)
T1 (T ≤ 2)	9 (10.5)
T2 (2 < T ≤ 5)	61 (70.9)
T3 (T > 5)	16 (18.6)
Lymph node status
Positive	36 (41.9)
Negative	50 (58.1)
Histological grades
І	17 (19.8)
П	46 (53.5)
Ш	23 (26.7)
ER statusa
Positive	40 (46.5)
Negative	46 (53.5)
CK5/6 expression
Positive	35 (40.7)
Negative	51 (59.3)
HER2 expressiona
Positive (IHC 3+/2+)	45 (19/26) (52.3)
Negative (IHC 0-1+)	41 (47.7)
HER2 gene statusb
Amplification	28 (32.6)
Non-amplification	58 (67.4)
Chemotherapy
No	37(43.0)
Yes	49(57.0)
Recurrence
No	51(59.3)
Yes	35(40.7)

^aER and HER2 was determined by immunohistochemical staining according to guideline [21]

^bHER2 gene was determined by fluorescent in situ hybridization (FISH) according to guideline [22]

HER2 human epidermal growth factor receptor-2, CK5/6 cytokeratin5/6, ER estrogen receptor