TABLE 2.
Pathogen | No. of pathogens identified; time to pathogen identification (mean ± SD) (h) using: |
P value (difference [h]) | |
---|---|---|---|
Conventional standard method | MALDI-TOF MS method | ||
All pathogens | 98; 135 ± 55 | 57; 71 ± 37 | <0.001 (64) |
Gram positivea | 60; 129 ± 26 | 32; 77 ± 47 | <0.001 (52) |
Gram negativeb | 35; 130 ± 32 | 24; 65 ± 17 | <0.001 (65) |
Staphylococcus spp. | 33; 127 ± 27 | 14; 90 ± 67 | <0.001 (37) |
Streptococcus spp. | 23; 132 ± 24 | 17; 64 ± 18 | <0.001 (68) |
Escherichia coli and Klebsiella spp. | 19; 130 ± 25 | 15; 63 ± 15 | <0.001 (67) |
Gram-negative pathogens other than E. coli and Klebsiella spp. | 16; 131 ± 39 | 9; 69 ± 21 | <0.001 (64) |
Includes Streptococcus spp. (viridans streptococci, S. pneumoniae, and other Streptococcus spp.) and Staphylococcus spp. (S. aureus and coagulase-negative staphylococci).
Escherichia coli, Klebsiella spp., Proteus spp., Pseudomonas spp., Acinetobacter baumannii, Citrobacter koseri, Enterobacter spp., Serratia marcescens, Haemophilus influenza, Burkholderia spp., Pasteurella multocida, and Fusobacterium species.