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. 2016 Apr 25;54(5):1259–1268. doi: 10.1128/JCM.02856-15

TABLE 2.

Sensitivity and specificity of the four ELISAs and IHAa

Assay Cutoff % Sensitivity for Thai melioidosis patients (n = 141) % Specificity for U.S. healthy donors (n = 90)
OPS-ELISA 0.41 82.3 85.6
0.46 80.9 90.0
0.66 75.2 95.6
0.87b 71.6 96.7
CPS-ELISA 0.55 61.7 85.6
0.75 56.0 90.0
0.95 48.2 95.6
1.18b 43.3 95.6
WC-ELISA 0.51 78.0 85.6
0.57 75.2 90.0
0.81 70.2 95.6
0.83b 70.2 95.6
CF-ELISA 0.54 80.9 85.6
0.61 78.0 91.1
0.73 73.7 95.6
0.97b 66.7 96.7
IHA 1:10 90.8 77.8
1:20 85.8 88.9
1:40 84.4 95.6
1:2,560b 26.2 100
a

The assay values were calculated from Thai melioidosis patients and U.S. healthy donors.

b

OD cutoff at 95% specificity when Thai donors were used as controls.