TABLE 2.
Sensitivity and specificity of the four ELISAs and IHAa
| Assay | Cutoff | % Sensitivity for Thai melioidosis patients (n = 141) | % Specificity for U.S. healthy donors (n = 90) |
|---|---|---|---|
| OPS-ELISA | 0.41 | 82.3 | 85.6 |
| 0.46 | 80.9 | 90.0 | |
| 0.66 | 75.2 | 95.6 | |
| 0.87b | 71.6 | 96.7 | |
| CPS-ELISA | 0.55 | 61.7 | 85.6 |
| 0.75 | 56.0 | 90.0 | |
| 0.95 | 48.2 | 95.6 | |
| 1.18b | 43.3 | 95.6 | |
| WC-ELISA | 0.51 | 78.0 | 85.6 |
| 0.57 | 75.2 | 90.0 | |
| 0.81 | 70.2 | 95.6 | |
| 0.83b | 70.2 | 95.6 | |
| CF-ELISA | 0.54 | 80.9 | 85.6 |
| 0.61 | 78.0 | 91.1 | |
| 0.73 | 73.7 | 95.6 | |
| 0.97b | 66.7 | 96.7 | |
| IHA | 1:10 | 90.8 | 77.8 |
| 1:20 | 85.8 | 88.9 | |
| 1:40 | 84.4 | 95.6 | |
| 1:2,560b | 26.2 | 100 |
The assay values were calculated from Thai melioidosis patients and U.S. healthy donors.
OD cutoff at 95% specificity when Thai donors were used as controls.