TABLE 4.
Comparison of combination results of four different ELISAs and each ELISA using serum samples from melioidosis patients, Thai healthy donors, U.S. healthy donors, tuberculosis patients, scrub typhus patients, and leptospirosis patientsa
| ELISA results | No. of serum samples (%) |
|||||
|---|---|---|---|---|---|---|
| Melioidosis (n = 141) | Thai healthy donors (n = 188) | U.S. healthy donors (n = 90) | Tuberculosis (n = 20) | Scrub typhus (n = 50) | Leptospirosis (n = 50) | |
| Positive for all ELISAs | 50 (35.5) | 1 (0.5) | 2 (2.2) | 0 | 1 (2.0) | 0 |
| Positive for any ELISA | 112 (79.4) | 17 (9.0) | 4 (4.4) | 0 | 4 (8.0) | 1 (2.0) |
| Positive for OPS-ELISA only | 7 (5.0) | 3 (1.6) | 0 | 0 | 2 (4.0) | 1 (2.0) |
| Positive for CPS-ELISA only | 1 (0.7) | 2 (1.1) | 0 | 0 | 0 | 0 |
| Positive for WC-ELISA only | 0 | 0 | 0 | 0 | 0 | 0 |
| Positive for CF-ELISA only | 1 (0.7) | 1 (0.5) | 0 | 0 | 1 (2.0) | 0 |
| Negative for all ELISAs | 29 (20.6) | 171 (91.0) | 86 (95.6) | 20 (100) | 46 (92.0) | 49 (98.0) |
a
The cutoff ODs used for OPS-ELISA, CPS-ELISA, WC-ELISA, and CF-ELISA were 0.87, 1.18, 0.83, and 0.97, respectively.