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. Author manuscript; available in PMC: 2016 Sep 28.
Published in final edited form as: Nature. 2016 Mar 28;532(7599):353–356. doi: 10.1038/nature17191

Figure 5. All eight stereoisomers of amino alcohols from enones.

Figure 5

a Access to all stereoisomers via reaction using (E)- or (Z)-4a with catalyst permutation in each step. Isolated yields are reported. Diastereomeric ratios (d.r.) were determined by NMR analysis using a crude reaction mixture. b HPLC traces of all stereoisomeric amino alcohol samples. See Supplementary Information for details.