Table 1.
Characteristics of kidney transplant recipients and allografts by DGF status
| ALL (N=671) | DGF (N=230) | No DGF (N=441) | P 1 | ||
|---|---|---|---|---|---|
| Recipient Characteristics | |||||
| Age, years | 54.7 (15) | 55.1 (13.7) | 54.4 (15.6) | 0.938 | |
| Male | 420 (63%) | 157 (68%) | 263 (60%) | 0.028 | |
| Black race | 288 (43%) | 116 (50%) | 172 (39%) | 0.005 | |
| Previous kidney transplant | 74 (11%) | 23 (10%) | 51 (12%) | 0.539 | |
| Cause of ESRD | Other or unknown | 113 (17%) | 38 (17%) | 75 (17%) | 0.512 |
| Diabetes | 202 (30%) | 77 (33%) | 125 (28%) | ||
| Hypertension | 192 (29%) | 67 (29%) | 125 (28%) | ||
| Glomerulonephritis | 117 (17%) | 35 (15%) | 82 (19%) | ||
| Graft failure | 47 (7%) | 13 (6%) | 34 (8%) | ||
| Panel reactive antibody | 0% | 464 (69%) | 165 (72%) | 299 (68%) | 0.217 |
| 1–20% | 48 (7%) | 18 (8%) | 30 (7%) | ||
| 21–80% | 93 (14%) | 23 (10%) | 70 (16%) | ||
| >80% | 66 (10%) | 24 (10%) | 42 (10%) | ||
| Pre-transplant dialysis | 614 (92%) | 219 (95%) | 395 (90%) | 0.013 | |
| Body mass index | 28.4 (5.8) | 29.4 (5.7) | 27.9 (5.8) | 0.002 | |
| Duration of dialysis before transplant, months2 | 59.1 (35.8) | 62.1 (33.3) | 57.4 (37) | 0.017 | |
| HLA mismatch level | 5 [4–5] | 5 [4–5] | 5 [4–5] | 0.019 | |
| Cold ischemia time, hours | 18 [14–22] | 19 [15–23] | 17 [13–22] | 0.008 | |
| Pump duration, hours | 10 [6–15] | 11 [7–15] | 10 [6–14] | 0.015 | |
| Allograft (Donor) Characteristics | |||||
| Age, years | 46.8 (13.7) | 46.7 (13) | 46.9 (14.1) | 0.446 | |
| Male | 415 (62%) | 153 (67%) | 262 (59%) | 0.072 | |
| Black race | 102 (15%) | 43 (19%) | 59 (13%) | 0.069 | |
| ECD | 205 (31%) | 56 (24%) | 149 (34%) | 0.012 | |
| DCD | 175 (26%) | 84 (37%) | 91 (21%) | <0.001 | |
| Kidney donor risk index | 1.4 [1.1–1.7] | 1.4 [1.2–1.6] | 1.4 [1.1–1.7] | 0.844 | |
| Kidney donor profile index, % 3 | 62 [40–79] | 61 [45–76.5] | 63 [38–81] | 0.849 | |
| Hypertension | 262 (39%) | 81 (35%) | 181 (41%) | 0.142 | |
| Diabetes | 73 (11%) | 19 (8%) | 54 (12%) | 0.116 | |
| Height, cm | 170.4 (11.1) | 170.6 (11.6) | 170.3 (10.9) | 0.520 | |
| Weight, kg | 83.3 (22.5) | 84.8 (25.3) | 82.5 (21) | 0.387 | |
| Stroke as cause of death | 289 (43%) | 90 (39%) | 199 (45%) | 0.137 | |
| Terminal serum creatinine, mg/dL | 1.22 (1.01) | 1.4 (1.29) | 1.12 (0.82) | 0.207 | |
Values are mean (SD), median [interquartile range], or n (%). DGF, delayed graft function; ESRD, end-stage renal disease; HLA, human leukocyte antigen; DCD, donation after circulatory determination of death; ECD, expanded criteria donor (defined as donor age ≥60 years or 50–59 years with 2 or more of the following risk factors: terminal serum creatinine >1.5 mg/dl, history or hypertension, stroke as the cause of death).
1
Wilcoxon rank sum test for continuous variables and Chi-Square test for categorical variables
2
Among those with pre-transplant dialysis
3
Relative to all US deceased donors in 2010