Table 4.
25(OH)D quartiles and binary CV risk factors at enrollment*
Unadjusted model |
Adjusted model 1† |
Adjusted model 2‡ |
||||
---|---|---|---|---|---|---|
CV risk factor | OR | 95% CI | OR | 95% CI | OR | 95% CI |
Hypertension | ||||||
Q2 | 0.84 | 0.58, 1.24 | 0.81 | 0.55, 1.21 | 0.83 | 0.55, 1.25 |
Q3 | 0.60§ | 0.41, 0.89§ | 0.66 | 0.43, 1.00 | 0.69 | 0.44, 1.06 |
Q4 | 0.43§ | 0.29, 0.65§ | 0.44§ | 0.28, 0.68§ | 0.49§ | 0.31, 0.77§ |
Diabetes mellitus | ||||||
Q2 | 1.14 | 0.56, 2.31 | 0.98 | 0.47, 2.03 | 0.93 | 0.43, 1.99 |
Q3 | 0.54 | 0.22, 1.22 | 0.52 | 0.21, 1.21 | 0.57 | 0.22, 1.35 |
Q4 | 0.81 | 0.37, 1.73 | 0.66 | 0.29, 1.45 | 0.71 | 0.31, 1.63 |
Hyperlipidemia | ||||||
Q2 | 0.87 | 0.55, 1.38 | 0.76 | 0.47, 1.22 | 0.80 | 0.49, 1.29 |
Q3 | 0.31§ | 0.17, 0.54§ | 0.28§ | 0.15, 0.51§ | 0.30§ | 0.16, 0.55§ |
Q4 | 0.48§ | 0.28, 0.79§ | 0.43§ | 0.24, 0.74§ | 0.50§ | 0.28, 0.87§ |
25(OH)D = 25-hydroxyvitamin D; CV = cardiovascular; OR = odds ratio; 95% CI = 95% confidence interval; Q = 25(OH)D quartile.
Adjusted model 1: controlled for age, season, white race, sex, and country (Korea, UK, US, or other), except for diabetes mellitus, which controls for age, white race, sex, and season only.
Adjusted model 2: controlled for same as model 1 plus body mass index.
Statistically significant.