Table 1. Baseline demographic and clinical characteristics of the study sample of Medicare-insured live donor kidney transplant recipients according to ABO compatibility.
ABOi (N =271) | A2i (N =62) | Compatible(N = 26504) | ||
---|---|---|---|---|
Recipient Characteristics | % or mean +/- SD | % or mean +/- SD | % or mean +/- SD | |
Age | * | |||
<=18 | 2.21 | 3.23 | 4.89 | |
19-30 | 14.02 | 19.35 | 15.74 | |
31-44 | 18.08 | 29.03 | 23.64 | |
45-59 | 32.84 | 17.74 | 29.51 | |
>=60 | 32.84 | 30.65 | 26.22 | |
Female sex | 37.64 | 41.94 | 40.45 | |
Race | ||||
White | 64.94 | 70.97 | 69.33 | |
Black | 20.66 | 17.74 | 17.71 | |
Other | 14.39 | 11.29 | 12.97 | |
BMI (kg/m2) | ||||
10 to 18.5 | 4.43 | 4.84 | 5.25 | |
18.5 to 25 | 33.21 | 40.32 | 34.64 | |
25 to 30 | 31.37 | 25.81 | 29.87 | |
>30 | 21.77 | 19.35 | 24.58 | |
Cause of ESRD | ||||
Diabetes | 23.25 | 19.35 | 22.15 | |
Glomerulonephritis | 17.34 | 33.87 | 21.18 | |
Hypertension | 15.13 | 12.90 | 18.19 | |
Polycystic kidney disease | 7.38 | 4.84 | 6.62 | |
Other | 36.90 | 29.03 | 31.87 | |
Previous transplant | 22.51‡ | 12.90 | 12.02 | |
Pretransplant dialysis | ||||
Preemptive | 15.87 | 11.29 | 16.66 | |
>0-24 | 35.06 | 37.10 | 41.24 | |
25-60 | 28.41 | 35.48 | 26.73 | |
>60 | 18.45 | 14.52 | 13.84 | |
Peak panel reactive antibody level | ‡ | |||
< 10 | 58.30 | 64.52 | 74.80 | |
10–79 | 20.30 | 20.97 | 16.47 | |
>=80 | 11.44 | 6.45 | 4.35 | |
Missing | 9.96 | 8.06 | 4.39 | |
HLA mismatches | ||||
Zero A, B, and DR | 10.33 | 6.45 | 8.30 | |
Zero DR | 18.82 | 8.06 | 18.44 | |
Cytomegalovirus | ||||
Recipient + / Donor + | 37.27 | 38.71 | 36.13 | |
Recipient + / Donor - | 25.83 | 20.97 | 19.21 | |
Recipient - / Donor + | 9.59 | 16.13 | 14.14 | |
Recipient - / Donor - | 17.34 | 17.74 | 18.10 | |
Year of Transplant | ‡ | * | ||
2000-2005 | 35.42 | 41.94 | 55.61 | |
2006-2011 | 64.58 | 58.06 | 44.39 | |
Donor Characteristics | ||||
Age, mean (SD), yr | 43.58 (12.12)‡ | 40.71 (11.97) | 39.97 (11.30) | |
Female | 60.52 | 66.13 | 59.84 | |
Race | ||||
White | 69.00 | 80.65 | 70.65 | |
Black | 17.34 | 11.29 | 15.71 | |
Other | 13.65 | 8.06 | 13.65 | |
Induction | 67.16 | 88.71‡ | 63.39 | |
Steroids at discharge | 74.91 | 75.81 | 72.71 | |
Maintenance ISx at discharge | ‡ | * | ||
Tacrolimus and MMF | 79.34 | 82.26 | 62.63 | |
Rapamycin-based | 5.17 | 1.61 | 9.95 | |
Other | 15.50 | 16.13 | 27.41 |
P-values for comparisons of trait distribution in ABOi or A2-to-O groups versus compatible transplants:
P-values:
P 0.002–0.04;
P 0.0001–0.001;
P < 0.0001