Skip to main content
. Author manuscript; available in PMC: 2017 May 1.
Published in final edited form as: Allergy. 2016 Mar 6;71(5):621–628. doi: 10.1111/all.12812

Figure 1.

Figure 1

Homology model of the Aed a 3 C-terminal region. (A) Sequence alignment between the apap fragment and Aed a 3 C-terminal region. The two conserved disulfide bridges are highlighted with the antigenic epitope region boxed in green. (B) X-ray structure of apap fragment (yellow) in complex with mouse FAB antibody consisting of a light chain (white) and a heavy chain (red). (C) Homology model of the Aed3 C-terminal region 187-253 with structurally conserved disulfide bridges. The antigenic epitope region is highlighted in green. (D) Electrostatic potential surface model of the Aed a 3 C-terminal region with the positively- and negatively-charged surfaces in blue and red, respectively.