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. Author manuscript; available in PMC: 2017 May 1.
Published in final edited form as: Dev Dyn. 2016 Mar 17;245(5):614–626. doi: 10.1002/dvdy.24399

Figure 2. cJUN is enriched in the promoters of upregulated mesenchyme genes and is expressed in intestinal ICM at E14.5.

Figure 2

(A) The top ten promoter enriched transcription factors (TF) identified by DiRE include known muscle regulators RP58, NF1, ZIC3 and the MEIS1/HOXA9 complex. Occurrence indicates the percentage of gene regulatory regions that contain a binding site for the specified TF. Significant TF are ranked according to importance (calculated as the product of TF occurrence and TF weight, as assigned by DiRE (Gotea and Ovcharenko, 2008)). In situ images from Genepaint.org (Set ID in brackets) of E14.5 intestinal cross sections for (B) RP58 (ZFP238) [MH813], (C) TAL1 [EH2794], (D) E47 (TCF3) [MH770], (E) NF1 [ES1724], (F) LDP1 (UBP1) [EN293], (G) ZID (ZBTB6) [MH3098], (H) ZIC3 [EB2075], (I) PAX4 [MH3124], (J) ROAZ (ZFP423) [MH1157], (K) JUN [MH524], (L) MEIS1 [EG1701], and (M) HOXA9 [EB2525].