Table 2.
Adverse effects of subchronic dose of aspirin on testicular cell population dynamics of rats.
| Groups | Germinal cell types | Interstitial cell types | ||||||
|---|---|---|---|---|---|---|---|---|
| Spermatogonia | Primary spermatocyte | Secondary spermatocyte | Spermatids | Fibroblast | Immature Leydig's cell | Mature Leydig's cell | Degenerating cell | |
| Vehicle control | 26.12 ± 0.76 | 20.25 ± 0.86 | 65.16 ± 3.16 | 160.19 ± 5.16 | 59.01 ± 1.32 | 51.33 ± 2.16 | 73.16 ± 1.06 | 16.36 ± 1.37 |
| 30-day treatment | 19.61 ± 1.73b | 12.25 ± 0.62c | 12.16 ± 1.26c | 5.19 ± 0.76c | 55.07 ± 2.31 | 30.33 ± 3.01c | 32.16 ± 3.05c | 70.16 ± 1.31c |
| 60-day treatment | 5.23 ± 0.36c,f | 2.25 ± 0.26c,f | 1.56 ± 0.96c,f | 2.19 ± 5.16c,f | 47.01 ± 2.32b | 21.33 ± 2.67c | 19.01 ± 1.06c,f | 81.12 ± 2.16c,f |
Data are means ± SEM (n = 7). b P ≤ 0.01; c P ≤ 0.001 compared to the respective control values and f P ≤ 0.001 compared to the respective values of the 30-day-treated group.